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 报告题目: Biomaterials capable of cell membrane modulation and selective in vivo labeling for drug delivery applications
  
 开始时间: 2018-07-24 15:30:00
  
 报告地点: 实验一楼第一会议室
  
 报 告 人: Prof. Jianjun Cheng
  
 主办单位: 材料科学与工程学院
  
 备    注:

报告人介绍

Biography :

2015        Full Professor, University of Illinois at Urbana Champaign

2011        Associate Professor, University of Illinois at Urbana Champaign

2005        Assistant Professor, University of Illinois at Urbana Champaign

2004        Post Doctorate, MIT

2001        Ph.D., University of California, Santa Barbara     

1996        M.S., Southern Illinois University

1993        B.S., Nankai University

PNAS,  2018, 115, 4903-4908.                                     

J. Am. Chem. Soc.,  2018, 140, 1235-1238.

Chem. Soc. Rev.,  2017, 46, 6570-6599                      

Nat. Chem. Biol., 2017, 13, 415-424.

Nat. Commun.,  2017, 8, 92.                                        

Nat. Chem.,   2017, 9, 614-622.

 J. Am. Chem. Soc.,  2016, 138, 9498-9507.                

Nature,  2016, 530, 71-76.

 

报告介绍

Abstract    

    I will present our work around design of helical polypeptides. I will report our design of helical, charged polypeptides, which has shown excellent cell membrane activity. By controlling the hydrogen bonding donor and acceptor properties, we can precisely tune the helicity of polypeptides. I will report the integration of Ring-opening metathesis polymerization and ring-opening polymerization of the amino acid N-carboxyanhydride to allow facile synthesis of amino acid N-carboxyanhydride was found and the polymerization of controlled by the brush polypeptide helices In the second portion of my talk, I will present sugar molecule mediated in vivo Cancer targeting.